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Antigenic Specificity | ESRRB - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that binds a canonical ESRRB recognition (ERRE) sequence 5'TCAAGGTCA-3' localized on promoter and enhancer of targets genes regulating their expression or their transcriptional activity. Plays a role, in a LIF-independent manner, in maintainance of self-renewal and pluripotency of embryonic and trophoblast stem cells through different signaling pathways including FGF signaling pathway and Wnt signaling pathways. Upon FGF signaling pathway activation, interacts with KDM1A by directly binding to enhancer site of ELF5 and EOMES and activating their transcription leading to self-renewal of trophoblast stem cells. Also regulates expression of multiple rod-specific genes and is required for survival of this cell type. Plays a |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse ESRRB |
Other Names | [steroid hormone receptor ERR2 isoform 2; Steroid hormone receptor ERR2; steroid hormone receptor ERR2; estrogen related receptor, beta; Estrogen receptor-like 2; Estrogen-related receptor beta; ERR-beta; Nuclear receptor subfamily 3 group B member 2] |
Gene, Accession # | [ESRRB], Gene ID: 26380, NCBI: NP_001152972.1, UniProt: Q61539 |
Catalog # | MBS3223680 |
Price | $335 |
Order / More Info | ESRRB - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |