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Antigenic Specificity | PAK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, hamster |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The PAK (p21 activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK activation have been reported. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N terminal region of PAK causes autophosphorylation and conformational change of PAK. More recently identified members PAK4, PAK5 and PAK6 have lower sequence similarity with PAK1 3 in the regulatory N terminal region. It has been demonstrated that phosphorylation of serine 474 of PAK4 may play a pivotal role in the activity and function of PAK4 kinase. |
Immunogen | Immunogen: PAK4 antibody was raised in Rabbit using synthetic peptide corresponding to the N-terminus of human Pak4 as the immunogen. |
Other Names | [Rabbit PAK4; PAK4; PAK4; PAK-4; p21 activated kinase; PAK4; PAK 4; PAK-4; PAK 4; PAK-4] |
Gene, Accession # | [PAK4], Gene ID: 10298, NCBI: CAA09820.1, UniProt: O96013 |
Catalog # | MBS5309110 |
Price | $705 |
Order / More Info | PAK4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |