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Antigenic Specificity | Cytochrome P450 2C8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Cytochrome P450 2C8 protein. Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).Romkes M., Biochemistry 30:3247-3255(1991).Ged C., Biochim. Biophys. Acta 1088:433-435(1991).Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human Cytochrome P450 2C8. |
Other Names | [Cytochrome P450 2C8; EC 1.14.14.1; CYPIIC8; P450 form 1; P450 MP-12/MP-20] |
Gene, Accession # | Gene ID: 1558, NCBI: NP_000761.3, UniProt: P10632 |
Catalog # | MBS9401848 |
Price | $200, $255 |
Order / More Info | Cytochrome P450 2C8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |