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Antigenic Specificity | TRAF3 |
Clone | [981] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1, CD40 receptor-associated factor 1(CRAF1), CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes, TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover, TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1, OTUB2 and OTUD5. |
Immunogen | Immunogen: Fusion protein of TRAF3 |
Other Names | [CAP 1; CAP-1; CAP1; CD40 associated protein 1; CD40 binding protein; CD40 bp; CD40 receptor associated factor 1; CD40 receptor-associated factor 1; CD40-binding protein; CD40BP; CRAF 1; CRAF1; IIAE5; LAP 1; LAP1; LMP1 associated protein; LMP1-associated protein 1; MIPT3; TNF receptor associated factor 3; TNF receptor-associated factor 3; TRAF 3; Traf3; TRAF3] |
Gene, Accession # | [TRAF3], Gene ID: 7187, NCBI: NP_001186356.1, UniProt: Q13114 |
Catalog # | MBS2542095 |
Price | $220, $290, $435 |
Order / More Info | TRAF3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |