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Antigenic Specificity | Human DNA-directed RNA polymerase III subunit RPC10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. |
Immunogen | Immunogen: Recombinant human DNA-directed RNA polymerase III subunit RPC10 protein(1-108aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-107955 |
Other Names | [RNA polymerase III subunit C10; DNA-directed RNA polymerase III subunit K; RNA polymerase III 12.5 kDa subunit; RNA polymerase III subunit C11; RPC11; My010; POLR3K], [POLR3K; POLR3K; C11; My010; RPC10; RPC11; RPC12.5; C11-RNP3; RPC11; RNA polymerase III subunit C10; RPC12.5; HsC11p; RPC11; hRPC11] |
Gene, Accession # | [RPC10], Gene ID: 51728, NCBI: NP_057394.3, UniProt: Q9Y2Y1 |
Catalog # | MBS968915 |
Price | $160, $235 |
Order / More Info | Human DNA-directed RNA polymerase III subunit RPC10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |