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Antigenic Specificity | TNFRSF18 |
Clone | [T9P4G4-D7] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects 25 kDa. Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2). |
Immunogen | Immunogen: Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18 Immunogen Species: Human |
Other Names | [Mouse Human TNFRSF18 IgG2b; TNFRSF18, Clone T9P4G4-D7; Activation inducible TNFR family receptor; AITR; CD357; GITR; GITRD; Glucocorticoid induced TNFR related protein; glucocorticoid-induced tnf receptor ligand; Glucocorticoid-induced TNFR-related protein; TNF receptor superfamily activation inducible protein; TNFRSF 18; TNR18_HUMAN; Tumor necrosis factor receptor superfamily member 18; Tumor necrosis factor receptor superfamily member 18 precursor] |
Gene, Accession # | [TNFRSF18], Gene ID: 8784, NCBI: NP_004186.1, UniProt: Q9Y5U5 |
Catalog # | MBS8001960 |
Price | $390 |
Order / More Info | TNFRSF18 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: TNFRSF18 tumor necrosis factor receptor superfamily, member 18. 2. Shimizu J. et al., (2002) Nat. Immunol. 3(2): 135-142. |