CEL (N-Epsilon)-Carboxyethyl-Lysine Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CEL (N-Epsilon)-Carboxyethyl-Lysine antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CEL (N-Epsilon)-Carboxyethyl-Lysine |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 0.05 mg |
| Concentration | 0.25 mg/ml |
| Applications | Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is suitable for the detection of CEL in tissues and tissue extracts. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) beta2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain tissues of patients |
| Immunogen | Immunogen: N-epsilon-(Carboxyethyl)-Lysine-BSA |
| Other Names | n/a |
| Gene, Accession # | [CEL] |
| Catalog # | MBS397066 |
| Price | $1475 |
| Order / More Info | CEL (N-Epsilon)-Carboxyethyl-Lysine Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Horiuchi S., Araki N., and Morino Y. (1991) Immunological approach to characterize advanced glycation end products of the Maillard reaction: Evidence for the presence of a common stucture. J. Biol. Chem. 266; 7329-7332. 2. McLellan AC, Thornalley PJ, Benn J, Sonksen PH (1994) Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications. Clinical Science 87: 21-29. 3. Ahmed MU, Brinkmann E, Degenhardt TP, Thorpe SR, Baynes JW (1997) Ne-(Carboxyethyl)lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins. Biochem J 324:565-570. 4. Degenhardt TP, Thorpe SR, Baynes JW (1998) Chemical modification of proteins by methylglyoxal. Cell Mol Biol 44:1139-1145. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies