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Antigenic Specificity | Neuropilin 1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. |
Immunogen | Immunogen: A synthesized peptide derived from human Neuropilin 1. Subcellular Localization: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and lo |
Other Names | [Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; CD304; NRP1; NRP; VEGF165R], [NRP1; NRP1; NP1; NRP; BDCA4; CD304; VEGF165R; NRP; VEGF165R] |
Gene, Accession # | [NRP1], Gene ID: 8829, NCBI: NP_001019799.1, UniProt: O14786 |
Catalog # | MBS179628 |
Price | $160, $340, $340 |
Order / More Info | Neuropilin 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |