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Antigenic Specificity | GPN1/XAB1 (DNA Repair & Protein Synthesis) |
Clone | [GPN1/2350] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-t |
Immunogen | Immunogen: Recombinant full-length human GPN1 protein Cellular Localization: Cytoplasmic & Nuclear |
Other Names | [ATP(GTP) binding protein (ATPBD1A); GPN-loop GTPase 1; GPN1; MBD2-interacting protein (MBDin); NTPBP; RNA polymerase II associated protein 4 (RPAP4); XPA-binding protein 1 (XAB1) GTPase] |
Gene, Accession # | [GPN1], Gene ID: 11321, NCBI: NP_001138519.1, UniProt: Q9HCN4 |
Catalog # | MBS4380431 |
Price | $190, $340, $340 |
Order / More Info | GPN1/XAB1 (DNA Repair & Protein Synthesis) Antibody from MYBIOSOURCE INC. |
Product Specific References | Nitta, M., et al. 2000. A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA. Nucleic Acids Res. 28: 4212-4218. |