EWSR1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEWSR1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, dog
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
ConcentrationSize: 100 ug/200 ul
ApplicationsELISA, Western Blot, Immunohistochemistry
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DescriptionThis antibody recognizes ~70 kDa of EWSR1 protein. It also cross reacts with human, mouse and rat tissues. The other species are not tested. The EWSR1 gene encodes a putative RNA binding protein. Mutation in this gene causes Ewing sarcoma and neuroectodermal and various other tumors. This gene is involved in a number of different sarcomas as a result of chromosomal translocations. EWSR1 is fused to an ETS transcription factor (FLI-1, ERG, ETV-1, E1AF or FEV) in Ewing sarcoma; to activating transcription factor-1 (ATF-1) in soft tissue clear cell sarcoma; to Wilms Tumor -1 (WT1) in desmoplastic small round cell; to nuclear receptor 4A3 (NR4A3) in extraskeletal myxoid chondrosarcoma, and to C/EBPhomologous protein (CHOP) in myxoid liposarcoma
ImmunogenAntigen Preparation: A synthetic peptide corresponding to the internal segment of EWSR1 protein. This sequence is identical among human, rat, mouse and dog species.
Other Namesn/a
Gene, Accession #[EWSR]
Catalog #MBS462243
Price$270
Order / More InfoEWSR1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesMelot,T., et al. Characterization of a new brain-specific isoform of the EWS oncoprotein. Eur. J. Biochem. 268 (12), 3483-3489 (2001)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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