RMP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRMP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total RMP protein. Involved in gene transcription regulation. Acts as a transcriptional repressor in concert with the corepressor UXT to regulate androgen receptor (AR) transcription. May act as a tumor suppressor to repress AR-mediated gene transcription and to inhibit anchorage-independent growth in prostate cancer cells. Required for cell survival in ovarian cancer cells. Together with UXT, associates with chromatin to the NKX3-1 promoter region. Antagonizes transcriptional modulation via hepatitis B virus X protein. Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human RMP.
Other Names[NNX3; RNA polymerase II subunit 5-mediating protein; RNA polymerase II; subunit 5-mediating protein; RPB5-mediating protein]
Gene, Accession #[RMP], Gene ID: 8725, NCBI: NP_001239570.1, UniProt: O94763
Catalog #MBS9408318
Price$200, $255
Order / More InfoRMP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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