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Antigenic Specificity | DOK3 (C-term), 293-321 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DOK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-321 amino acids from the C-terminal region of human DOK3. DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate Abl function (By similarity). |
Immunogen | n/a |
Other Names | [Docking protein 3; Downstream of tyrosine kinase 3; DOK3] |
Gene, Accession # | [DOK3], Gene ID: 79930, NCBI: NP_001138347.1, UniProt: Q7L591 |
Catalog # | MBS9210919 |
Price | $165, $370 |
Order / More Info | DOK3 (C-term), 293-321 Antibody from MYBIOSOURCE INC. |
Product Specific References | Berger, A.H., et al. Nat. Genet. 42(3):216-223(2010) Senis, Y.A., et al. J. Thromb. Haemost. 7(10):1718-1726(2009) Honma, M., et al. Genes Cells 11(2):143-151(2006) Robson, J.D., et al. Mol. Cell. Biol. 24(6):2332-2343(2004) Favre, C., et al. Genes Immun. 4(1):40-45(2003) |