Pin1 (Phospho-Ser16) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Pin1 (Phospho-Ser16) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Pin1 (Phospho-Ser16) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of Pin1 only when phosphorylated at serine 16. Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.Lee YC, et al. (2013)J Cell Sci 126, 4862-72. Ando K, et al. (2013 |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine16(R-M-S(p)-R-S) derived from Human Pin1. |
| Other Names | [PPIase Pin1; Rotamase Pin1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; EC 5.2.1.8] |
| Gene, Accession # | [Pin1], Gene ID: 5300, NCBI: NP_006212.1, UniProt: Q13526 |
| Catalog # | MBS9404889 |
| Price | $200, $255 |
| Order / More Info | Pin1 (Phospho-Ser16) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies