NPHS2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NPHS2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat. |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008] |
| Immunogen | Immunogen: Rabbit polyclonal NPHS2 antibody was raised against a peptide from near the C terminal residues of human NPHS2 protein. |
| Other Names | [NPHS2 protein; Podocin; podocin; nephrosis 2, idiopathic, steroid-resistant (podocin)], [NPHS2; NPHS2; PDCN; SRN1] |
| Gene, Accession # | [NPHS2], Gene ID: 7827, NCBI: AAH29141.1 |
| Catalog # | MBS415609 |
| Price | $230 |
| Order / More Info | NPHS2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | (1) Tonna,S., Wang,Y.Y., Wilson,D., et al.The R229Q mutation in NPHS2 may predispose to proteinuria in thin-basement-membrane ephropathy.Pediatr. Nephrol.23 (12), 2201-2207(2008). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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