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Antigenic Specificity | ST5 (C-term), 1106-1137 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.34 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ST5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1106-1137 amino acids from the C-terminal region of human ST5. ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. |
Immunogen | n/a |
Other Names | [Suppression of tumorigenicity 5 protein; DENN domain-containing protein 2B; HeLa tumor suppression 1; ST5; DENND2B; HTS1] |
Gene, Accession # | [ST5], Gene ID: 6764, NCBI: NP_005409.3, UniProt: P78524 |
Catalog # | MBS9212280 |
Price | $165, $370 |
Order / More Info | ST5 (C-term), 1106-1137 Antibody from MYBIOSOURCE INC. |
Product Specific References | Majidi, M., et al., J. Biol. Chem. 275(9):6560-6565 (2000). Hubbs, A.E., et al., Oncogene 18(15):2519-2525 (1999). Majidi, M., et al., J. Biol. Chem. 273(26):16608-16614 (1998). Lichy, J.H., et al., Nucleic Acids Res. 24(23):4700-4708 (1996). Lichy, J.H., et al., Cell Growth Differ. 3(8):541-548 (1992). |