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Antigenic Specificity | AKR1C3 (Center), 107-135 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the Central region of human AKR1C3. This gene encodes a member of the aldo/keto reductasesuperfamily, which consists of more than 40 known enzymes andproteins. These enzymes catalyze the conversion of aldehydes andketones to their corresponding alcohols by utilizing NADH and/orNADPH as cofactors. The enzymes display overlapping but distinctsubstrate specificity. This enzyme catalyzes the reduction ofprostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and theoxidation of 9alpha,11beta-PGF2 to PGD2. It may play an importantrole in the pathogenesis of allergic diseases such as a |
Immunogen | n/a |
Other Names | [Aldo-keto reductase family 1 member C3; 1---; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II; brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Indanol dehydrogenase; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; AKR1C3; DDH1; HSD17B5; KIAA0119; PGFS] |
Gene, Accession # | [AKR1C3], Gene ID: 8644, NCBI: NP_001240837.1, UniProt: P42330 |
Catalog # | MBS9207258 |
Price | $165, $370 |
Order / More Info | AKR1C3 (Center), 107-135 Antibody from MYBIOSOURCE INC. |
Product Specific References | Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010) Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) : Zakharov, V., et al. Int J Clin Exp Pathol 3(6):608-617(2010) |