VPS53 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VPS53 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | VPS53 Antibody: The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist. |
| Immunogen | Immunogen: VPS53 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human VPS53. Buffer: VPS53 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [VPS53; HCCS1; hVps53L; pp13624; Vacuolar protein sorting-associated protein 53 homolog; vacuolar protein sorting 53 homolog (S. cerevisiae)], [VPS53; VPS53; HCCS1; PCH2E; hVps53L; pp13624] |
| Gene, Accession # | [VPS53], Gene ID: 55275, NCBI: EAW90658, UniProt: Q5VIR6 |
| Catalog # | MBS150579 |
| Price | $375 |
| Order / More Info | VPS53 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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