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Antigenic Specificity | ARHGEF25 |
Clone | [934] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GEFT, also named as p63RhoGEF, may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. GETF links specifically G alpha q/11-coupled receptors to RHOA activation. GEFT may be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. It is involved in skeletal myogenesis. |
Immunogen | Immunogen: Fusion protein of GEFT |
Other Names | [ARHGEF25; ARHGP; GEFT; Guanine nucleotide exchange factor GEFT; p63RhoGEF; RAC/CDC42 exchange factor; Rac/Cdc42/Rho exchange factor GEFT; Rho guanine nucleotide exchange factor 25; RhoA/RAC/CDC42 exchange factor; RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT] |
Gene, Accession # | [ARHGEF25], Gene ID: 115557, NCBI: NP_001104740.1, UniProt: Q86VW2 |
Catalog # | MBS2541925 |
Price | $220, $290, $435 |
Order / More Info | ARHGEF25 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |