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Antigenic Specificity | WT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. |
Immunogen | Immunogen: Recombinant human Wilms tumor protein (1-449AA) |
Other Names | [WT33; WT1] |
Gene, Accession # | [WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544 |
Catalog # | MBS7103070 |
Price | $160, $235 |
Order / More Info | WT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |