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Antigenic Specificity | AChR alpha3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AChR alpha3 antibody detects endogenous levels of total AChR alpha3. Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Subunit Structure: Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly (PubMed:16120769). Interacts with LYPD6 (PubMed:27344019). The heteropentamer alpha-3-beta-2 interacts with alpha-conotoxins ImI and ImII (PubMed:15609996). The heteropentamer alpha-3-beta-2 interacts with a |
Immunogen | Immunogen: A synthesized peptide derived from human AChR alpha3 Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane. Cell Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit Similarity: Pig (100%), Bovine (91%), Horse (91%), Sheep (100%), Rabbit (82%) |
Other Names | [ACHA3_HUMAN; AChR; Cholinergic receptor neuronal nicotinic alpha polypeptide 3; Cholinergic receptor nicotinic alpha 3; Cholinergic receptor nicotinic alpha polypeptide 3; CHRNA 3; CHRNA3; LNCR2; MGC104879; NACHRA 3; NACHRA3; Neuronal acetylcholine receptor protein alpha 3 chain precursor; Neuronal acetylcholine receptor subunit alpha 3; Neuronal acetylcholine receptor subunit alpha-3; Neuronal nicotinic acetylcholine receptor alpha 3 subunit; PAOD2] |
Gene, Accession # | [CHRNA3], Gene ID: 1136, NCBI: NP_000734.2, UniProt: P32297 |
Catalog # | MBS9608819 |
Price | $240, $280 |
Order / More Info | AChR alpha3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |