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Antigenic Specificity | Adrenergic Receptor alpha-2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total Adrenergic Receptor alpha-2B protein. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.Lomasney J.W., Proc. Natl. Acad. Sci. U.S.A. 87:5094-5098(1990).Weinshank R.L., Mol. Pharmacol. 38:681-688(1990).Small K.M., J. Biol. Chem. 276:4917-4922(2001). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human Adrenergic Receptor alpha-2B. |
Other Names | [ADA2B; ADRA2L1; ADRA2RL1; ADRARL1; ALPHA2BAR] |
Gene, Accession # | Gene ID: 151, NCBI: NP_000673.2, UniProt: P18089 |
Catalog # | MBS9405670 |
Price | $200, $255 |
Order / More Info | Adrenergic Receptor alpha-2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |