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Antigenic Specificity | Insulin Receptor, beta (IRb) (BSA & Azide Free) |
Clone | [3F224] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | no preservative |
Size | 0.1 mL |
Concentration | 1mg/ml |
Applications | Suitable for use in ELISA, Immunoprecipitation, Tyrosine Kinase Assays and for Affinity Purification with peptide elution. Other applications have not been tested. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes autophosphorylated and unoccupied human receptors as well as the receptor-insulin complex. Does not affect insulinstimulated autophosphorylation. Species Cross reactivity: Mouse and Rat. The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a b-a-a-b configuration. The b-subunit (95kD) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the a-subunit (135kD) is completely extracellular. |
Immunogen | Immunogen: A 15-mer synthetic peptide corresponding to aaTyr-KKNGRILTLPRSNPS from the C-terminal of human insulin receptor Beta-subunit. Cellular Localization: Cell membrane Epitope: GRVLTLPRS (within the C-terminus). MW of Antigen: 95kD. Grade: Affinity Purified |
Other Names | [-Insulin Receptor, beta (IRb) (BSA & Azide Free)], [INSR; INSR; HHF5; CD220; IR] |
Gene, Accession # | Gene ID: 3643, NCBI: NP_000199.2, UniProt: P06213 |
Catalog # | MBS632478 |
Price | $775 |
Order / More Info | Insulin Receptor, beta (IRb) (BSA & Azide Free) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |