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Antigenic Specificity | KANK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total KANK2 protein. Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus. May be involved in promotion of cell proliferation.Nagase T., DNA Res. 7:143-150(2000).Ota T., Nat. Genet. 36:40-45(2004).Olsen J.V., Cell 127:635-648(2006). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human KANK2. |
Other Names | [Ankyrin repeat domain-containing protein 25; SRC-1-interacting protein; SRC1-interacting protein; Matrix-remodeling-associated protein 3] |
Gene, Accession # | [KANK2], Gene ID: 25959, NCBI: NP_001129663.1, UniProt: Q63ZY3 |
Catalog # | MBS9414209 |
Price | $200, $255 |
Order / More Info | KANK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |