Edit |   |
---|---|
Antigenic Specificity | CXCR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 2(CXCR2) detection. Tested with WB in Human. Background: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family(subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human CXCR2 (196-212aa CYEDMGNNTANWRMLLR), different from the related mouse sequence by six amino acids. |
Other Names | [C-X-C chemokine receptor type 2(CXC-R2/CXCR-2); chemokine(C-X-C motif) receptor 2; C-X-C chemokine receptor type 2; CD 182; CD182; CD182 antigen; CDw128b; Chemokine(CXC) receptor 2; CMKAR2; CXC-R2; CXCR 2; CXCR-2; CXCR2; CXCR2_HUMAN; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL 8 receptor type 2; IL 8R B; IL-8 receptor type 2; IL-8R B; IL8 RB; IL8 receptor type 2; IL8R B; IL8R2; IL8RA; Interleukin 8 Receptor B], [CXCR2; CXCR2; CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; IL8RB; CXC-R2; CXCR-2; IL-8R B] |
Gene, Accession # | [CXCR2], Gene ID: 3579, NCBI: P25025.2, UniProt: P25025 |
Catalog # | MBS175134 |
Price | $280 |
Order / More Info | CXCR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |