TOR1A Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTOR1A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Western blot analysis of extracts of various cell lines, using TOR1A antibody. The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5).
ImmunogenImmunogen: Recombinant protein of human TOR1A
Other Names[torsin-1A; Torsin-1A; torsin-1A; torsin family 1 member A; Dystonia 1 protein; Torsin ATPase-1A (EC:3.6.4.-); Torsin family 1 member A], [TOR1A; TOR1A; DQ2; DYT1; DQ2; DYT1; TA; TORA]
Gene, Accession #[TOR1A], Gene ID: 1861, NCBI: NP_000104.1, UniProt: O14656
Catalog #MBS419965
Price$385
Order / More InfoTOR1A Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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