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Antigenic Specificity | TOR1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using TOR1A antibody. The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5). |
Immunogen | Immunogen: Recombinant protein of human TOR1A |
Other Names | [torsin-1A; Torsin-1A; torsin-1A; torsin family 1 member A; Dystonia 1 protein; Torsin ATPase-1A (EC:3.6.4.-); Torsin family 1 member A], [TOR1A; TOR1A; DQ2; DYT1; DQ2; DYT1; TA; TORA] |
Gene, Accession # | [TOR1A], Gene ID: 1861, NCBI: NP_000104.1, UniProt: O14656 |
Catalog # | MBS419965 |
Price | $385 |
Order / More Info | TOR1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |