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Antigenic Specificity | PARL |
Clone | [8C4B2; 1H12E10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Purified recombinant fragment of PARL (aa112-167) expressed in E Coli. |
Other Names | [PSARL; PSARL1; RHBDS1], [PSARL; PSARL1; RHBDS1] |
Gene, Accession # | [PARL], Gene ID: 55486, NCBI: NP_001311366.1 |
Catalog # | MBS475833 |
Price | $335 |
Order / More Info | PARL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |