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Antigenic Specificity | LRRFIP1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins. Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5?-AGCCCCCGGCG-3?) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
Immunogen | Immunogen: Purified recombinant human LRRFIP1 protein fragments expressed in E Coli. Cellular Localization: Nucleus; Cytoplasm |
Other Names | [GC-binding factor 2 TAR RNA-interacting protein], [GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1] |
Gene, Accession # | [LRRFIP1], Gene ID: 9208, NCBI: NP_001131022.1, UniProt: Q32MZ4 |
Catalog # | MBS857910 |
Price | $300 |
Order / More Info | LRRFIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |