LRRFIP1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLRRFIP1
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins. Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5?-AGCCCCCGGCG-3?) and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
ImmunogenImmunogen: Purified recombinant human LRRFIP1 protein fragments expressed in E Coli. Cellular Localization: Nucleus; Cytoplasm
Other Names[GC-binding factor 2 TAR RNA-interacting protein], [GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1]
Gene, Accession #[LRRFIP1], Gene ID: 9208, NCBI: NP_001131022.1, UniProt: Q32MZ4
Catalog #MBS857910
Price$300
Order / More InfoLRRFIP1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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