Smad3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySmad3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatantigen affinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration4mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionReceptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and
ImmunogenImmunogen: Recombinant human Mothers against decapentaplegic homolog 3 protein Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Other Names[HSPC193; HST17436; LDS3; Mad protein homolog; MAD; MADH3; SMA and MAD related protein 3; SMAD family member 3; SMAD; mothers against DPP homolog 3; Smad3]
Gene, Accession #[Smad3], Gene ID: 4088
Catalog #MBS2541745
Price$110, $150, $225
Order / More InfoSmad3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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