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Antigenic Specificity | DAPK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in regulation of starvation-induced autophagy. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A; the inhibition of SMPP1M functions to enhance muscle responsiveness to |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DAPK3 (NP 001339.1). |
Other Names | [DLK; ZIP; ZIPK] |
Gene, Accession # | [DAPK3], Gene ID: 1613, NCBI: NP_001339.1, UniProt: O43293 |
Catalog # | MBS8549740 |
Price | $280 |
Order / More Info | DAPK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |