PTPN5 (N-term), 1-30 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PTPN5 (N-term), 1-30 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PTPN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PTPN5. STEP (Protein-tyrosine phosphatase striatum-enriched) is a neural-specific protein-tyrosine phosphatase. It is also known as PTPN5 (tyrosine-protein phosphatase, non-receptor type 5). STEP immunoreactive areas are most intense in the regions of the CNS receiving a dopaminergic input (e.g. striatum, basal ganglia). STEP is part of the NMDA receptor (R) complex and inhibits NMDAR single-channel activity and NMDAR-mediated synaptic current. Phosphorylation of STEP, via D1 and PKA activation by dopamine, decreases the activity of STEP by reducing its affinity for substrate. |
| Immunogen | n/a |
| Other Names | [Tyrosine-protein phosphatase non-receptor type 5; Neural-specific protein-tyrosine phosphatase; Striatum-enriched protein-tyrosine phosphatase; STEP; PTPN5] |
| Gene, Accession # | [PTPN5], Gene ID: 84867, NCBI: NP_001035059.1, UniProt: P54829 |
| Catalog # | MBS9213154 |
| Price | $165, $370 |
| Order / More Info | PTPN5 (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kurup, P., et al. J. Neurosci. 30(17):5948-5957(2010) Rose, J. Phd, et al. Mol. Med. (2010) In press : Korff, S., et al. BMC Cancer 8, 329 (2008) : Eswaran, J., et al. Biochem. J. 395(3):483-491(2006) Nguyen, T.H., et al. J. Biol. Chem. 277(27):24274-24279(2002) |
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MYBIOSOURCE INC.
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