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Antigenic Specificity | LDLR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LDLR antibody detects endogenous levels of total LDLR. Function: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.Similarity: The NPXY motif mediates the interaction with the clathrin adapter DAB2 and with LDLRAP1 which are involved in receptor internalization. A few residues outside the motif also play a role in the interaction. Belongs to the LDLR family. |
Immunogen | Immunogen: A synthesized peptide derived from human LDLR, corresponding to a region within the internal amino acids. |
Other Names | [FH; FHC; LDL R; LDL receptor; LDLCQ2; Ldlr; LDLR_HUMAN; Low Density Lipoprotein Receptor; Low density lipoprotein receptor class A domain containing protein 3; Low density lipoprotein receptor familial hypercholesterolemia; Low-density lipoprotein receptor] |
Gene, Accession # | [LDLR], Gene ID: 3949, NCBI: NP_000518.1, UniProt: P01130 |
Catalog # | MBS9608278 |
Price | $240, $280 |
Order / More Info | LDLR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |