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Antigenic Specificity | DAB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human, Mouse ,Rat; other species are not tested. Please decide the specificity by homology. Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domai |
Immunogen | Immunogen: Disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) |
Other Names | [DAB2, Disabled homolog 2, DOC 2, DOC2, FLJ26626], [DAB2; DAB2; DOC2; DOC-2; DOC2; DOC-2] |
Gene, Accession # | [DAB2], Gene ID: 1601, NCBI: NP_001231800.1, UniProt: P98082 |
Catalog # | MBS768460 |
Price | $265 |
Order / More Info | DAB2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |