DAB2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDAB2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionSpecificity: Human, Mouse ,Rat; other species are not tested. Please decide the specificity by homology. Adapter protein that functions as clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containg non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits. Can function in clathrin-mediated endocytosis independently of the AP-2 complex. Involved in endocytosis of integrin beta-1; this function seems to redundant with the AP-2 complex and seems to require DAB2 binding to endocytosis accessory EH domai
ImmunogenImmunogen: Disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
Other Names[DAB2, Disabled homolog 2, DOC 2, DOC2, FLJ26626], [DAB2; DAB2; DOC2; DOC-2; DOC2; DOC-2]
Gene, Accession #[DAB2], Gene ID: 1601, NCBI: NP_001231800.1, UniProt: P98082
Catalog #MBS768460
Price$265
Order / More InfoDAB2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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