IRE1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRE1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.59-0.68 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), IMM, Western Blot (WB)
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DescriptionAffinity Purified Serine/Threonine-protein kinase/endoribonuclease IRE1 Antibody. Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
ImmunogenImmunogen: Synthetic peptide corresponding to unique amino acid sequence within amino acid region 900-1000 on human IRE1A protein. Immunoglobulin: IgG. Expression: Ubiquitously expressed. High levels observed in pancreatic tissue.
Other Names[Endoplasmic reticulum (ER) to nucleus signalling 1 Endoribonuclease ER to nucleus signaling 1; ERN 1; hIRE 1p Inositol requiring 1 Inositol requiring protein 1 IRE 1 IRE 1a IRE 1P Ire1 alpha; IRE1P MGC163277 MGC163279 Protein kinase/endoribonuclease RGD1559716 Serine/threonine protein kinase/endoribonuclease IRE1], [ERN1; ERN1; IRE1; IRE1P; IRE1a; hIRE1p; hIRE1p; IRE1a]
Gene, Accession #[IRE1], Gene ID: 2081, NCBI: O75460.2, UniProt: O75460
Catalog #MBS540804
Price$390
Order / More InfoIRE1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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