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Antigenic Specificity | RNASE1 (N-term), 14-42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RNASE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RNASE1. This gene encodes a member of the pancreatic-type ofsecretory ribonucleases, a subset of the ribonuclease Asuperfamily. The encoded endonuclease cleaves internalphosphodiester RNA bonds on the 3'-side of pyrimidine bases. Itprefers poly(C) as a substrate and hydrolyzes 2',3'-cyclicnucleotides, with a pH optimum near 8.0. The encoded protein ismonomeric and more commonly acts to degrade ds-RNA over ss-RNA.Alternative splicing occurs at this locus and four transcriptvariants encoding the same protein have been identified. [providedby RefSeq]. |
Immunogen | n/a |
Other Names | [Ribonuclease pancreatic; HP-RNase; RIB-1; RNase UpI-1; Ribonuclease 1; RNase 1; Ribonuclease A; RNase A; RNASE1; RIB1; RNS1] |
Gene, Accession # | [RNASE1], Gene ID: 6035, NCBI: NP_002924.1, UniProt: P07998 |
Catalog # | MBS9205381 |
Price | $165, $370 |
Order / More Info | RNASE1 (N-term), 14-42 Antibody from MYBIOSOURCE INC. |
Product Specific References | D'Alessio, G. Biopolymers 91(12):989-994(2009) Kover, K.E., et al. J. Mol. Biol. 379(5):953-965(2008) Ueki, M., et al. Biochem. Genet. 46 (3-4), 145-153 (2008) : Johnson, R.J., et al. Biochemistry 46(36):10308-10316(2007) Cybulski, C., et al. Urol. Int. 79(1):44-49(2007) |