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Antigenic Specificity | XIAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.2 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti XIAP recognizes XIAP (X-linked inhibitor of apoptosis protein) also known as IAP-3 (Inhibitor of apoptosis protein 3) or BIRC (baculoviral IAP repeat-containing protein 4). XIAP is an E3 ubiquitin ligase and acts as an endogenous inhibitor of cell death by suppressing caspases 3, 7, and 9 activities. The protein is also reported to play a role in the activation of the NF-kappa-B cell signaling pathway and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). In addition to acting as an ubiquitin ligase XIAP has also been reported to have NEDD8 E3 ligase activity.XIAP has been identified as a potential tumor marker. In addition, aberrant XIAP regulation has been implicated in neurodegenerative and autoimmunity |
Immunogen | n/a |
Other Names | [E3 ubiquitin-protein ligase XIAP; E3 ubiquitin-protein ligase XIAP; E3 ubiquitin-protein ligase XIAP; X-linked inhibitor of apoptosis; Baculoviral IAP repeat-containing protein 4; IAP-like protein; ILP; hILP; Inhibitor of apoptosis protein 3; IAP-3; hIAP-3; hIAP3; X-linked inhibitor of apoptosis protein; X-linked IAP], [XIAP; XIAP; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; API3; BIRC4; IAP3; ILP; hILP; IAP-3; hIAP-3; hIAP3; X-linked IAP] |
Gene, Accession # | [XIAP], Gene ID: 331, NCBI: P98170.2, UniProt: P98170 |
Catalog # | MBS224958 |
Price | $375 |
Order / More Info | XIAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |