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Antigenic Specificity | IFIH1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of Jurkat cell lines, using IFIH1 antibody. Immunofluorescence analysis of U2OS cell using IFIH1 antibody. Blue: DAPI for nuclear staining. Antiviral innate immunity depends on the combination of parallel pathways triggered by virus detecting proteins in the Toll-like receptor (TLR) family and RNA helicases, such as Rig-I (retinoic acid-inducible gene I) and MDA-5 (melanoma differentiation-associated antigen 5), which promote the transcription of type I interferons (IFN) and antiviral enzymes (1-3). TLRs and helicase proteins contain sites that recognize the molecular patterns of different virus types, including DNA, single-stranded RNA (ssRNA), double-stranded RNA (dsRNA), and glycoproteins. T |
Immunogen | Immunogen: Recombinant protein of human IFIH1 |
Other Names | [IFIH1 protein, partial; Interferon-induced helicase C domain-containing protein 1; interferon-induced helicase C domain-containing protein 1; interferon induced with helicase C domain 1; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116] |
Gene, Accession # | [IFIH1], Gene ID: 64135, NCBI: AAH78180.1 |
Catalog # | MBS4150052 |
Price | $385 |
Order / More Info | IFIH1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |