Human CD49e Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD49e
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b
Formataffinity purified
Size0.1 mg
Concentration100ug/200ul
ApplicationsFlow Cytometry (FC/FACS)
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DescriptionSpecificity: Human CD49e. CD49e is the integrin beta5 chain, a 135/25 kDa heterodimer, that associates noncovalently with CD29, the integrin beta1 subunit, to form the beta5beta1 very late antigen-5 (VLA-5) complex, a very well established fibronectin receptor that is expressed on many cell types, including thymocytes, T cells, monocytes and platelets. Expression of the VLA-5 heterodimer is increased on activated and memory T cells. It is also found on very early B cells and on activated B lymphocytes. CD49e/CD2-mediated binding to fibronectin provides a costimulatory signal to T cells. It also enhances FcgammaR-and complement receptor-mediated phagocytosis, and is involved in monocyte migration into extracellular tissues.
Immunogenn/a
Other Names[CD49e-VLA-5]
Gene, Accession #[CD49e]
Catalog #MBS4152202
Price$445
Order / More InfoHuman CD49e Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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