alpha 5 beta 1 Integrin (Volociximab), Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | alpha 5 beta 1 Integrin (Volociximab), Human |
| Clone | [M200] |
| Host Species | n/a |
| Reactive Species | human |
| Isotype | IgG4, kappa |
| Format | Protein A purified |
| Size | 0.2 mg |
| Concentration | n/a |
| Applications | ELISA (EIA); Flow Cytometry (FC/FACS); Immunofluorescence (IF); Block; Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody to detect alpha 5 beta 1 Integrin in human samples. The antibody binds specifically to a5beta1 integrin; which is part of the superfamily of glycoprotein transmembrane receptors for ligands such as fibronectin; vitronectin; laminins and collagens. The a5beta1 integrin receptor plays a key role in cellular processes such as inflammation; cell proliferation; angiogenesis and tumour metastasis. Comprising the variable domain of the original mouse antibody; a chimeric mouse:human IgG4 version of this antibody has been tested in vivo: In cynomolgus monkeys with laser-induced choroidal neovascularization (CNV); in rabbit models and in human volunteers. The antibody reached Phase II clinical trials with PDL Biopharma and Biogen |
| Immunogen | Immunogen: Heterodimeric alpha5beta1Fc fusion protein |
| Other Names | [Fibronectin receptor; CD49 antigen-like family member E; Integrin alpha-F; VLA-5; CD49e], [ITGA5; ITGA5; FNRA; CD49e; VLA-5; VLA5A; FNRA] |
| Gene, Accession # | [ITGA5], Gene ID: 3678, NCBI: NP_002196.4, UniProt: P08648 |
| Catalog # | MBS845970 |
| Price | $655 |
| Order / More Info | alpha 5 beta 1 Integrin (Volociximab), Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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