Human Transcription factor EB Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Transcription factor EB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Acts as a positive regulator of autophagy by promoting expression of genes involved in autophagy. Specifi |
| Immunogen | Immunogen: Recombinant human Transcription factor EB protein (1-220aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-11004 / sc-11005 / sc-48784 |
| Other Names | [Class E basic helix-loop-helix protein 35; bHLHe35; TFEB; BHLHE35], [TFEB; TFEB; TCFEB; BHLHE35; ALPHATFEB; BHLHE35; bHLHe35] |
| Gene, Accession # | [TFEB], Gene ID: 7942, NCBI: NP_001161299.2, UniProt: P19484 |
| Catalog # | MBS1493040 |
| Price | $120, $160 |
| Order / More Info | Human Transcription factor EB Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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