RBCK1 (UBCE7IP3) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRBCK1 (UBCE7IP3)
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein A purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionE3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates. Functions as an E3 ligase for oxidized IREB2 and both heme and oxygen are necessary for IREB2 ubiquitination. Promotes ubiquitination of TAB2 and IRF3 and their degradation by the proteasome. Component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes wit
ImmunogenImmunogen: This RBCK1 (UBCE7IP3) antibody is generated from a mouse immunized with a recombinant protein of human RBCK1 (UBCE7IP3).
Other Names[XAP3; XAP4; HOIL1; PBMEI; PGBM1; RBCK2; RNF54; HOIL-1; ZRANB4; C20orf18; UBCE7IP3]
Gene, Accession #[RBCK1], Gene ID: 10616, NCBI: NP_112506.2, UniProt: Q9BYM8
Catalog #MBS8558609
Price$280
Order / More InfoRBCK1 (UBCE7IP3) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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