CD18 / IntegrinBeta-2 (ITGB2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD18 / IntegrinBeta-2 (ITGB2) |
| Clone | [68-5A5] |
| Host Species | Mouse |
| Reactive Species | human. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions. |
| Immunogen | Immunogen: Stimulated human leukocytes |
| Other Names | [Beta 2 (antigen CD18 (p95); CD18; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150; Complement component 3 receptor 3 and 4 subunit; Complement receptor C3 beta subunit; Integrin beta-2 (ITGB2); LAD; LCAMB; Leukocyte Cell Adhesion Molecule CD18; Lymphocyte function associated antigen 1 (LFA1); MAC1; Macrophage antigen 1 (mac1) beta], [ITGB2; ITGB2; LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18; MFI7] |
| Gene, Accession # | [ITGB2], Gene ID: 3689, NCBI: NP_000202.3, UniProt: P05107 |
| Catalog # | MBS439122 |
| Price | $190, $340, $340 |
| Order / More Info | CD18 / IntegrinBeta-2 (ITGB2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Leucocyte Typing III, (ed. McMichael AJ et. al.), Oxford Univ. Press, Oxford, 1987 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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