GSK3A (Center) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGSK3A (Center)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat (predicted reactivity: human, Xenopus)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis GSK3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 348-382 amino acids from the Central region of human GSK3A. Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the develop
Immunogenn/a
Other Names[Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3A]
Gene, Accession #[GSK3A], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840
Catalog #MBS9208349
Price$165, $370
Order / More InfoGSK3A (Center) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHe X.,et al.Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases. Hoshino T.,et al.Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases. Grimwood J.,et al.Nature 428:529-535(2004). Nikoulina S.E.,et al.Diabetes 49:263-271(2000). Phiel C.J.,et al.Nature 423:435-439(2003).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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