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Antigenic Specificity | PARL |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PARL antibody detects endogenous levels of total PARL. Description: PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.Function: Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of O |
Immunogen | Immunogen: Purified recombinant fragment of human PARL expressed in E. Coli Subcellular Location: Mitochondrion Inner Membrane and Nucleus. Translocated into the nucleus by an unknown mechanism. |
Other Names | [Mitochondrial intramembrane cleaving protease PARL; Mitochondrial intramembrane-cleaving protease PARL; P-beta; parl; PARL_HUMAN; Pbeta; presenilin associated rhomboid-like; Presenilins associated rhomboid-like protein; PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1; Rhomboid 7 homolog 1] |
Gene, Accession # | [PARL], Gene ID: 55486, NCBI: NP_001032728.1, UniProt: Q9H300 |
Catalog # | MBS9602789 |
Price | $235, $295, $370 |
Order / More Info | PARL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |