PARL Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPARL
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: PARL antibody detects endogenous levels of total PARL. Description: PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.Function: Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of O
ImmunogenImmunogen: Purified recombinant fragment of human PARL expressed in E. Coli Subcellular Location: Mitochondrion Inner Membrane and Nucleus. Translocated into the nucleus by an unknown mechanism.
Other Names[Mitochondrial intramembrane cleaving protease PARL; Mitochondrial intramembrane-cleaving protease PARL; P-beta; parl; PARL_HUMAN; Pbeta; presenilin associated rhomboid-like; Presenilins associated rhomboid-like protein; PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1; Rhomboid 7 homolog 1]
Gene, Accession #[PARL], Gene ID: 55486, NCBI: NP_001032728.1, UniProt: Q9H300
Catalog #MBS9602789
Price$235, $295, $370
Order / More InfoPARL Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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