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Antigenic Specificity | Integrin beta 4 (CD104) |
Clone | [58XB4] |
Host Species | Mouse (Balb/c) |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC), Immunofluorescence (IF), Immunohistochemistry (IHC) (frozen), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Binds specifically to integrin beta4 chain(CD104) or beta4 integrin, that associates with integrin alpha6 (CD49f) forms alpha6/beta4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells (especially on the prolifeRative basal layer epithelial cells in skin), endothelial cells, Schwann cells, certain tumor cells and a subset of pre-T cells. CD104 (Cluster of Differentiation 104) is also known as Integrin, beta 4 (ITGB4). CD104 is a 205 kD type I transmembrane glycoprotein. Integrins are heterodimers composed of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specifici |
Immunogen | Source Note: 58XB4 is a monoclonal antibody obtained by immunization of Balb/c mice with Integrin beta4. The immunogen used to raise this antibody was the full length CD104 protein. |
Other Names | [integrin beta-4 isoform 1; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150], [ITGB4; ITGB4; CD104] |
Gene, Accession # | Gene ID: 3691, NCBI: NP_000204.3, UniProt: P16144 |
Catalog # | MBS570278 |
Price | $415 |
Order / More Info | Integrin beta 4 (CD104) Antibody from MYBIOSOURCE INC. |
Product Specific References | Dirk Geerts, Lionel Fontao, Mirjam G. Nievers, Roel Q.J. Schaapveld, Patricia E. Purkis, Grant N. Wheeler, E. Birgitte Lane, Irene M. Leigh, and Arnoud Sonnenberg. J Cell Biol. 1999 October 18; 147(2): 417-434. |