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Antigenic Specificity | Ezrin (Phospho-Tyr353) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunoblotting (IB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human Ezrin only when phosphorylated at tyrosine 353. Ezrin (also known as cytovillin or villin-2) is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. The N-terminal FERM domain strongly binds sodium-hydrogen exchanger regulatory factor (NHERF) proteins (involving long-range allostery). The C-terminal ERM domain binds to actin, phosphatidylinositol(4,5)bis-phosphate (PIP2) and membrane prot |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from human Ezrin and conjugated to KLH. |
Other Names | [ezrin; Ezrin; ezrin; ezrin; Cytovillin; Villin-2; p81], [EZR; EZR; CVL; CVIL; VIL2; HEL-S-105; VIL2] |
Gene, Accession # | Gene ID: 7430, NCBI: NP_001104547.1, UniProt: P15311 |
Catalog # | MBS191074 |
Price | $340 |
Order / More Info | Ezrin (Phospho-Tyr353) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |