Ezrin (Phospho-Tyr353) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityEzrin (Phospho-Tyr353)
Clonepolyclonal
Host Speciesn/a
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsImmunoblotting (IB), Immunohistochemistry (IHC)
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DescriptionThis antibody detects endogenous human Ezrin only when phosphorylated at tyrosine 353. Ezrin (also known as cytovillin or villin-2) is encoded by the EZR gene. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. The N-terminal FERM domain strongly binds sodium-hydrogen exchanger regulatory factor (NHERF) proteins (involving long-range allostery). The C-terminal ERM domain binds to actin, phosphatidylinositol(4,5)bis-phosphate (PIP2) and membrane prot
ImmunogenAntigen: Peptide sequence that includes phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from human Ezrin and conjugated to KLH.
Other Names[ezrin; Ezrin; ezrin; ezrin; Cytovillin; Villin-2; p81], [EZR; EZR; CVL; CVIL; VIL2; HEL-S-105; VIL2]
Gene, Accession #Gene ID: 7430, NCBI: NP_001104547.1, UniProt: P15311
Catalog #MBS191074
Price$340
Order / More InfoEzrin (Phospho-Tyr353) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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