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Antigenic Specificity | HAAO - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against HAAO. It was validated on Western Blot using a cell lysate as a positive control.Target Description: 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and infl |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAAO |
Other Names | [3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilic acid dioxygenase] |
Gene, Accession # | [HAAO], Gene ID: 23498, NCBI: NP_036337, UniProt: P46952 |
Catalog # | MBS3206330 |
Price | $335 |
Order / More Info | HAAO - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |