Human CD86 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD86
Clone[4ABU63]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size50 tests, 100 tests
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Western Blot (WB)
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DescriptionCD86 also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors.It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B7-1.is an important accessory molecule in T cell costimulation via it's interaciton with CD28 and CD152/CTLA4.Since CD86 has rapid kinetics of induction.it is believed to be the major CD28 ligand expressed early in the immune response.it is also found on malignant Hodgkin and Reed Sternberg(HRS) cells in Hodgkin's disease.
Immunogenn/a
Other Names[CD86, partial; T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; CD86 molecule; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen: CD86]
Gene, Accession #[CD86], Gene ID: 942, NCBI: CAG46642.1, UniProt: P42081
Catalog #MBS8501761
Price$280, $300
Order / More InfoHuman CD86 Antibody from MYBIOSOURCE INC.
Product Specific References1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York. 2. Lanier LL. et al. (1991) J. Immunol. 146:4421-4426. 3. Campbell, JJ et al. (2001) J. Immunol. 166:6477-6482. 4. Cooper MD et al. (2001) Trends in Immunol. 22:633-640. 5. Galandrini R et al. (2002) Blood. 100:4581-4589.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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