CD11a inhibitor Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD11a inhibitor |
| Clone | [NKI(SPV)-L15] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody NKI(SPV)-L15 reacts with the alpha chain of LFA-1, the CD11a/CD18 integrin heterodimer present on Human T- and B-lymphocytes, granulocytes and monocytes. The antibody was selected for inhibition of T-cell mediated killing. Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a Human gene which functions in the immune system. It is involved in cellular adhesion and costimulatory signaling. ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte functio |
| Immunogen | Source Note: NKI(SPV)-L15 was obtained by immunization of BALB/c mice with cells of the T4+T8- cytotoxic T lymphocyte clone HG-38; the antibodies were selected for inhibition of T cell mediated killing by screening of the hybridoma supernatants 10-14 days after the fusion. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS570263 |
| Price | $415 |
| Order / More Info | CD11a inhibitor Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cytoplasmic Tails of beta1, beta2 and beta7 integrins differentially regulate LFA-1 function in K562 cells. M.Lub, S.J van Vliet, S.P.M.A Oomen, R.A Pieters, M. Robinson, C.G Figdor, Y van Kooyk. Mol. Biol of the Cell, Vol 8, 719-728, April 1997. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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