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Antigenic Specificity | Mouse IL-4 receptor |
Clone | [16F23] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects mouse IL-4R in Western blotting. Two types of IL-4 receptor complexes have been described. The typeI IL-4 receptor complex is composed of a high-affinity IL-4-binding subunit (referred to as IL-4 R or IL-4 R alpha) and the common gamma chain that does not bind IL-4 by itself. The type II IL-4 receptor complex is composed of IL-4 R and IL-13 R alpha 1. Besides IL-4 signals, the type II IL-4 receptor complex can also transduce IL-13 signals. In the type II complex, IL-4 R subunit binds only IL-4 and not IL-13. Similarly, the IL-13 R alpha 1 subunit binds only IL-13 and not IL-4. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-4R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [mouse Interleukin-4 Receptor (#16F23)], [Il4ra; Il4r; Il4r; CD124; Il4ra; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; Soluble IL-4 receptor subunit alpha; Soluble IL-4R-alpha; sIL4Ralpha/prot; IL4-BP] |
Gene, Accession # | [IL-4 receptor], Gene ID: 16190, NCBI: NP_001008700.1, UniProt: P16382 |
Catalog # | MBS690881 |
Price | $490 |
Order / More Info | Mouse IL-4 receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |