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Antigenic Specificity | ARNT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Recombinant protein of human ARNT (NP 001659.1). |
Other Names | [aryl hydrocarbon receptor nuclear translocator isoform 4; Aryl hydrocarbon receptor nuclear translocator; aryl hydrocarbon receptor nuclear translocator; aryl hydrocarbon receptor nuclear translocator; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta] |
Gene, Accession # | [ARNT], Gene ID: 405, NCBI: NP_001184254.1, UniProt: P27540 |
Catalog # | MBS8569393 |
Price | $280 |
Order / More Info | ARNT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |